Events List

Event date:
Monday, December 10, 2012 - 3:30pm to 4:30pm
Event location:
Center for Sensorimotor Neural Engineering, Russell Hall, Suite 204, 1414 NE 42nd St., Seattle, WA

The CSNE will sponsor the seminar "What is the Central Problem of Motor Control?" by Francisco J. Valero-Cuevas, PhD, Professor, Department of Biomedical Engineering and Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA.

Abstract:

Understanding the coevolutionary process that led to organisms as we know them is critical to understanding their function, dysfunction and rehabilitation. In recent decades, the perspective that muscle redundancy is the central problem of motor control has dominated this scientific endeavor. Therefore the "problem" the brain solves is cast explicitly and/or implicitly as one of neural computation needed to select viable solutions from the many allowed by the redundancy/adaptability that comes from having "too many" redundant or overcomplete muscles or joints. However valuable and informative, this perspective is also paradoxical with respect to the evolutionary process, the clinical reality that even mild injury leads to measurable dysfunction, and a rigorous mechanical analysis of complex systems and complex behavior. I will describe my personal journey in the study of sensorimotor function (biased towards mechanics, computational motor control, mathematics and clinical problems) that has allowed me to begin to articulate the problem of motor control in a way that resolves these apparent paradoxes. Namely, that vertebrates have barely enough muscles to meet the mechanical requirements of real-world ecological task.

Event date:
Thursday, December 6, 2012 - 3:30pm
Event location:
UW, Room EEB-105

The University of Washington Department of Computer Science & Engineering will host Dr. Yoky Matsuoka (founding Director of the CSNE; now at "Nest").  Dr. Matsuoka will present a seminar titled "Robots and Thermostats: More in Common Than You'd Think."

Abstract:  The first industrial robots were created as a tool for assembling cars, but in recent years, they've evolved to take on ever more important roles - including replacing parts of the human body - and capabilities, such as the ability to be controlled by the human brain. Similarly, the traditional thermostat started out as a simple switch on the wall. Using the similar approaches to creativity and intelligence that's been applied to the field of robotics, Nest has transformed the thermostat into a sexy, energy-saving device that gives us a glimpse into the home of the future.

Event date:
Thursday, December 6, 2012 - 3:00pm to 4:00pm
Event location:
Room G-417, HSB, University of Washington, Seattle, WA

Dr. Larry Sorenson will present the UW Computational Neuroscience Seminar titled "Correlation, Coherence, and Causality in Human Cortex."

ABSTRACT:  I will describe the work that we have been doing analyzing LFPs and SFP's. The LFP's were measured using a 10x10 grid with 400 micron electrode separation. The SFP's were measured using a 4x4 grid with 1 mm electrode separation. The spatial resolution is comparable to the size of the cortical columns. I will describe the relationships between the time domain, the frequency domain, and causality.

Event date:
Wednesday, December 5, 2012 - 3:30pm to 4:30pm
Event location:
Russell Hall, Suite 204, 1414 NE 42nd St., Seattle, WA

Dr. Hugh Herr, Associate Professor, Program of Media Arts and Sciences and Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology (Cambridge, MA) will present a seminar titled "The Importance of Neuromechanical Limb Models in the Design of Leg Prostheses and Orthoses.”

Abstract:  A long-standing goal in rehabilitation science is to apply neuromechanical principles of human movement to the development of highly functional prostheses and orthoses.  Critical to this effort is the development of actuator technologies that behave like muscle, device architectures that resemble the body’s own musculoskeletal design, and control methodologies that exploit principles of biological movement.  In this lecture, I discuss how agonist-antagonist actuation, polyarticular limb architecture, and reflex behaviors can result in quiet, stable, and economical legged mechanisms for walking and running.  Neuromechanical models are presented to examine the importance of limb morphology and neural control on locomotor performance.  These models are then used to motivate design strategies for prosthetic and orthotic mechanisms.

Event date:
Monday, November 26, 2012 - 3:30pm
Event location:
HSB, T-747, University of Washington

UW Neurobiology and Behavior will sponsor a seminar by Jan Marino "Nino" Ramirez, PhD (Professor, Department of Neurological Surgery;  Director, Center of Integrative Brain Research, Seattle Children's Research Institute;  Research Affiliate, Center on Human Development and Disability; University of Washington) titled "How clouds of neurons control rhythmic behavior."

Event date:
Friday, November 9, 2012 - 2:30pm to 3:30pm
Event location:
Kane Hall 210, University of Washington, Seattle, WA

Dr. Adrienne Fairhall, CSNE faculty member, will present "Information transmission in neurons and networks" as the speaker for the MathAcrossCampus Lecture.

Abstract:
The brain is often thought of as a computer, taking in and transforming information into new forms that allow it to drive actions. How does one mathematically quantify how information is represented in neural systems? We show that in many sensory systems, information is represented efficiently, even at the level of single neurons, and that properties of single neurons can dramatically affect the way in which information at different timescales is propagated through neural networks.
 

Event date:
Thursday, November 1, 2012 - 3:30pm to 4:30pm
Event location:
CSNE, Russell Hall, Suite 204, 1414 NE 42nd St., Seattle, WA

The CSNE will sponsor the seminar “Biohybrid Systems: Nerves, Machines & Interfacesby Ranu Jung, Ph.D., Professor, Department of Biomedical Engineering, Florida International University.

Abstract

The integration of technology with biology makes us more productive in the workplace, makes medical devices more effective, and makes our entertainment systems more engaging. Real-time communication between a nervous system and a device is now possible, but full and reliable integration in biohybrid systems is still far from reality. Improving the quality, quantity and reliability of the information that can be transferred between the engineered and biological systems is one important challenge. Other key developments in biohybrid systems have been in the biomimetic design of sensors, actuators and adaptive algorithms that may enhance their ability to integrate with endogenous biological processes. Biohybrid systems of the future are likely to utilize biomimetic machines with multi-channel, high throughput interfaces not only to integrate with the biological system, but to close the loop in a manner that promotes adaptation in the nervous system.

This talk will present some of our work that uses tools and techniques from computational neuroscience and neural engineering to develop biohybrid systems. A neural model of spinal pattern generating circuitry of lower vertebrates was characterized extensively and used to design neuromorphic controllers. These controllers have been interfaced with an active spinal cord, used to adaptively control an orthosis that could allow mobility after lower limb trauma in people and to adaptively control movement using neuromuscular electrical stimulation of paralyzed muscles in a rodent model of movement therapy after incomplete spinal cord injury. In other work, we are developing and deploying neural-enabled prosthetic systems to provide amputees with technology that is highly functional and easy to use. These efforts are directed at developing effective and reliable peripheral neural interfaces that can record motor intent of upper limb amputees and use electrical stimulation to provide them with sensory feedback.

Event date:
Monday, October 29, 2012 - 3:30pm to 4:30pm
Event location:
CSNE, 1414 NE 42nd St., Suite 204, Seattle, WA

The Center for Sensorimotor Neural Engineering will host a seminar by Dr. Vivian Mushahwar, Professor, University of Alberta ("Restoring Function after Neural Injury or Disease using Novel Applications of Electrical Stimulation") on Monday, October 29, 2012 at 3:30 pm.  The seminar will be held in Russell Hall, 1414 NE 42nd St., Suite 204, Seattle, WA.

Abstract:  The overall goal of our work is to develop interventions for improving function after neural injury or disease and alleviating some of the secondary complications associated with these conditions.  In this talk I will describe part of our work in preventing the formation of pressure ulcers, a serious complication associated with immobility and lack of sensation, using intermittent electrical stimulation.  This surface electrical stimulation approach produces postural shifts by inducing periodical muscle contractions in those who are unable to move on their own. The periodical contractions prevent excessive mechanical deformation of the muscle and restore oxygenation, which in turn prevent the breakdown of tissue.  I will also describe some of our efforts in restoring standing and walking after spinal cord injury using intraspinal microstimulation.  This approach involves the implantation of very fine wires inside the spinal cord, below the level of a lesion, and passing minute electrical currents to produce functional leg movements.  Long durations of weight-bearing standing and propulsive over ground walking could be achieved using this approach. The above are but two neuroprosthetic-based interventions in various phases of preparation for translation to the clinic. Other neuroprosthetic interventions are also under development in our group and show great promise for clinical implementation.  I will share my vision regarding the path of such interventions from discovery to market and the important role these approaches play in the improvement of human health.

Event date:
Tuesday, October 23, 2012 - 10:30am
Event location:
Hogness Auditorium, Health Sciences Bldg., University of Washington

The University of Washington Department of Biochemistry is happy to announce 2012 Nobel Prize in Chemistry awardee Dr. Brian K. Kobilka will present a seminar titled "Structural insights into the dynamic process of GPCR activation."  Dr. Kobilka is a professor in the Departments of Molecular and Cellular Physiology at Stanford University School of Medicine and co-founder of ConfometRx, a biotechnology company focusing on G-protein-coupled receptors. He was named a member of the National Academy of Sciences in 2011.  More information about the Nobel Prize for Brian Kobilka can be found at:
 

http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2012/#
 

Event date:
Tuesday, October 23, 2012 - 10:30am
Event location:
415 GUGGENHEIM HALL, University of Washington

The Computational Neuroscience program will sponsor a special seminar "Are You Afraid of the Dark Matter? Making Sense of Fluctuating Brain Activity" by Jean-Philippe Thivierge, University of Ottawa.

Abstract:  Most of the brain's activity occurs in the absence of direct stimuli, leading researchers to talk about the "dark energy" of the brain. Recent work has begun to characterize this spontaneous activity, and found that it follows highly non-random laws. In this talk, I will explore some of the characteristics of spontaneous activity and discuss its broader consequences for information processing in the brain.

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